Tui announced a “small number” of flight cancellations and delays in a blow to travel plans at the start of the midterm break.
The travel company said “various operational and supply chain issues” are behind the flight cancellations.
It canceled three flights from Birmingham, two flights from Gatwick and one from Manchester.
It comes after airline EasyJet announced it would cancel more than 200 flights over the next 10 days.
EasyJet said the cancellations would affect around 24 flights a day departing London Gatwick Airport between May 28 and June 6.
A Tui spokesperson said: “We apologize for the inconvenience caused to customers who have experienced flight delays or flight cancellations.
“Delays have been caused due to a combination of factors and we are doing everything we can to keep customers informed, and will provide refreshments and, where appropriate, provide hotel accommodation.
“Where we have made the difficult decision to cancel a small number of flights, customers will receive a full refund within 14 days and we will contact them directly to help them try to find alternative holidays.
“We would like to thank our customers for their understanding and apologize for the inconvenience caused.”
EasyJet said earlier its 200 cancellations were “necessary to provide reliable services during this busy time”.
It comes after a software crash forced EasyJet to cancel around 200 flights on Thursday.
A spokeswoman for the airline said in a statement: “We have made the decision to cancel in advance approximately 24 Gatwick flights per day from May 28 until June 6.
“We apologize for the late notice of some of these cancellations and the inconvenience caused to customers booked on these flights, but we believe this is necessary to provide reliable services during this busy time.
“Customers are notified from today (Friday) and have the option to rebook their flight or receive a refund and can claim compensation in accordance with the regulations.
“Over the next week we will operate around 1,700 flights a day, around a quarter of which to and from Gatwick.”
Elsewhere, Liverpool FC supporters traveling to the Champions League final and families embarking on mid-term jaunts faced long queues at the Port of Dover and UK airports.
Thousands of fans descended on the port of Kent on Friday to board cross-Channel ferries en route to Paris for Saturday’s game.
Airline passengers were also stuck in long queues at airports including Gatwick, Manchester, Stansted and Bristol.
There is also a strong demand for cruises from families embarking on mid-continent trips.
The port advised passengers to “pack adequate provisions, including food and water”, as it expects “a very busy week ahead”.